ARNTL antibody (Internal Region)

Catalog No. ABIN335124

Product Details anti-ARNTL Antibody

Target: ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

Binding Specificity: Internal Region

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This ARNTL antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: BMAL1 / ARNTL

Sequence: REKITTNCYK FKIKD

Specificity: This antibody is expected to recognize both reported isoforms (NP_001025444.1, NP_001025443.1). Reported variants represent identical protein (NP_001025443.1, NP_001169.3).

Cross-Reactivity: Cow, Dog, Human, Mouse, Pig, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Grade: Verified

Immunogen: Peptide with sequence REKITTNCYKFKIKD, from the internal region of the protein sequence according to NP_001169.3, NP_001025444.1.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx. 70+75 kDa bands observed in Human Brain (Cerebellum) lysates (calculated MW of 68.7 kDa according to NP_001169.3 and 64.1 kDa according to NP_001025444.1). Recommended concentration: 0.3-1 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:8000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for ARNTL

Target: ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

Alternative Name: ARNTL (ARNTL Products)

Synonyms: BMAL1 antibody, BMAL1c antibody, JAP3 antibody, MOP3 antibody, PASD3 antibody, TIC antibody, bHLHe5 antibody, Bmal1 antibody, ARNTL antibody, xBmal1 antibody, arntl antibody, Arnt3 antibody, BMAL1b antibody, bmal1b' antibody, aryl hydrocarbon receptor nuclear translocator like antibody, aryl hydrocarbon receptor nuclear translocator-like antibody, aryl hydrocarbon receptor nuclear translocator like S homeolog antibody, ARNTL antibody, Arntl antibody, arntl.S antibody, arntl antibody

Background: ARNTL, BMAL1, aryl hydrocarbon receptor nuclear translocator-like, BMAL1c, JAP3, MGC47515, MOP3, PASD3, TIC, ARNT-like protein 1, brain and muscle, bHLH-PAS protein JAP3, basic-helix-loop-helix-PAS orphan MOP3, member of PAS superfamily 3

Gene ID: 406, 11865, 29657

NCBI Accession: NP_001169, NP_001025444

Pathways: Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Warburg Effect