BID antibody (N-Term)

Catalog No. ABIN336094

This Mouse Monoclonal antibody specifically detects BID in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for BID antibody (N-Term) (ABIN336094)

Target: BID (BH3 Interacting Domain Death Agonist (BID))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BID antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: 4D3

Product Details anti-BID Antibody

Binding Specificity: AA 1-195, N-Term

Specificity: The antibody recognizes human BID. Other species not tested.

Characteristics: Synonyms: p22 BID, BH3-interacting domain death agonist

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human BID (aa 1-195) purified from E. coli

Isotype: IgG1

Application Details

Application Notes: ELISA. Western blot (1,000 - 2,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for BID

Target: BID (BH3 Interacting Domain Death Agonist (BID))

Alternative Name: BID

Background: BID is a pro-apoptotic Bcl-2 protein containing only the BH3 domain. In response to apoptotic signaling, BID interacts with another Bcl-2 family protein, Bax, leading to the insertion of Bax into the outer mitochondrial membrane. Bax is believed to induce the opening of the mitochondrial voltage-dependent anion channel. This results in the release of cytochrome c and other pro-apoptotic factors from the mitochondria leading to activation of caspases.Synonyms: BH3-interacting domain death agonist, p22 BID

Gene ID: 637

UniProt: P55957

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity