OGG1 antibody (AA 282-297)

Catalog No. ABIN337126

Product Details anti-OGG1 Antibody

Target: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Binding Specificity: AA 282-297

Reactivity: Human, Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This OGG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Mouse OGG1.

Predicted Reactivity: Percent identity with other species by BLAST analysis: Mouse (100%), Rat (88%), Hamster (88%), Elephant (88%), Panda (88%), Bovine (88%), Human (81%), Gorilla (81%), Monkey (81%), Dog (81%), Horse (81%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-HPKTSQAKGPSPLANK from an internal region of mouse OGG1 (NP_035087.2). Percent identity with other species by BLAST analysis: Mouse (100%), Rat (88%), Hamster (88%), Elephant (88%), Panda (88%), Bovine (88%), Human (81%), Gorilla (81%), Monkey (81%), Dog (81%), Horse (81%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (2.5 μg/mL), Peptide-ELISA (1:128000), WB (1:128000, 0.1 - 0.3 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 2.5 μg/mL.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for OGG1

Target: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Alternative Name: OGG1 (OGG1 Products)

Synonyms: OGG1 antibody, zgc:158858 antibody, 8-oxoguanine-DNA glycosylase 1 antibody, ARABIDOPSIS 8-OXOGUANINE-DNA GLYCOSYLASE 1 antibody, ATOGG1 antibody, F8K7.14 antibody, F8K7_14 antibody, 19.m02329 antibody, DDBDRAFT_0184479 antibody, DDBDRAFT_0233024 antibody, DDB_0184479 antibody, DDB_0233024 antibody, ogg1 antibody, Tb04.1H19.930 antibody, HMMH antibody, HOGG1 antibody, MUTM antibody, OGH1 antibody, Mmh antibody, 8-oxoguanine DNA glycosylase antibody, 8-oxoguanine DNA glycosylase L homeolog antibody, 8-oxoguanine-DNA glycosylase 1 antibody, 8-OXOGUANINE DNA GLYCOSYLASE antibody, putative 8-oxoguanine DNA glycosylase antibody, 8-oxoguanine DNA-glycosylase antibody, N-glycosylase/DNA lyase OGG1 antibody, 8-oxoguanine DNA-glycosylase 1 antibody, OGG1 antibody, ogg1.L antibody, ogg1 antibody, ECU08_0770 antibody, CA_C2707 antibody, BBOV_I004290 antibody, Smp_074010.1 antibody, LOC9329243 antibody, Tb927.4.2480 antibody, Ogg1 antibody

Background: Name/Gene ID: OGG1

Synonyms: OGG1, 8-oxoguanine DNA glycosylase, AP lyase, HMMH, N-glycosylase/DNA lyase, HOGG1, OGH1, OGG1 type 1f, MMH, MUTM

Gene ID: 4968

NCBI Accession: NP_035087

UniProt: O15527

Pathways: DNA Damage Repair