LRP1 antibody

Catalog No. ABIN337392

The Mouse Monoclonal anti-LRP1 antibody (Clone 5A6) (ABIN337392) specifically detects LRP1 in WB, IHC, FACS and IHC (p). The antibody is reactive with Human, Mouse and Rabbit samples.

Quick Overview for LRP1 antibody (ABIN337392)

Target: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Reactivity: Human, Mouse, Rabbit

Host: Mouse

Clonality: Monoclonal

Conjugate: This LRP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 5A6

Product Details anti-LRP1 Antibody

Specificity: Recognises the 85  kDa cleaved fragment of Low Density LRP (extracellular domain).

Purification: Protein A purified

Immunogen: Full length native protein (purified) (Human).

Type of Immunogen: Native protein

Isotype: IgG2b

Application Details

Application Notes: Approved: Flo, IHC, IHC-P (10 μg/mL), WB

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.05 M sodium phosphate, 0.1 M sodium chloride, 1 mM EDTA,  pH 6.6.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for LRP1

Target: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Alternative Name: LRP1 / CD91

Background: Name/Gene ID: LRP1

Synonyms: LRP1, Apolipoprotein E receptor, CD91 antigen, CD91, A2MR, IGFBP3R, Alpha-2-macroglobulin receptor, TGFBR5, Type V tgf-beta receptor, APOER, APR, LRP, LRP-1

Gene ID: 4035

UniProt: Q07954

Pathways: Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling