CD14 antibody (AA 33-44)

Catalog No. ABIN343171

This Mouse Monoclonal antibody specifically detects CD14 in FACS and Agon. It exhibits reactivity toward Human.

Quick Overview for CD14 antibody (AA 33-44) (ABIN343171)

Target: CD14

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD14 antibody is un-conjugated

Application: Flow Cytometry (FACS), Agonist (Agon)

Clone: BiG4

Product Details anti-CD14 Antibody

Binding Specificity: AA 33-44

Specificity: Soluble and membrane bound human CD14. The antibody don't block LPS binding to membrane bound CD14.

Purification: Protein A affinity column

Immunogen: human Monocytes

Isotype: IgG2a

Application Details

Application Notes: no significant inhibition of LPS binding to CD14

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with bidistilled water

Concentration: 1 mg/mL

Buffer: PBS, pH 7.8

Preservative: Without preservative

Storage: -20 °C,-80 °C

Target Details for CD14

Target: CD14

Alternative Name: CD14

Background: Background: biG 4 represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, weekly at surface of neutrophiles like Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 Molecule has been reported to be a receptor for endotoxin. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for LPS-LBP (lipopolysaccharide binding protein)-complexes.

Molecular Weight: ~50kDa

Gene ID: 929

NCBI Accession: NP_000582

UniProt: P08571

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades