NGFR antibody
Quick Overview for NGFR antibody (ABIN350715)
Target
See all NGFR AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- Mouse monoclonal antibody to p75NTR (ME20.4)
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Specificity
- Specific for p75NTR.
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Cross-Reactivity
- Cat, Dog, Human, Marmoset, Pig, Rabbit
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Purification
- Affinity purified
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Immunogen
- Human melanoma cell lines
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Isotype
- IgG1, IgG1 kappa
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anti-Nerve Growth Factor Receptor (NGFR) (AA 301-400) antibody
NGFR Reactivity: Human, Rat, Mouse WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Rat WB, IHC, ELISA Host: Mouse Monoclonal unconjugated
anti-Nerve Growth Factor Receptor (NGFR) (AA 281-421) antibodyNGFR Reactivity: Human IHC, Diff, StM Host: Mouse Monoclonal NGFR-1964 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) (AA 188-203), (Extracellular) antibodyKO Validated NGFR Reactivity: Human WB, IHC, FACS, IF, IP, IC, LCI Host: Rabbit Polyclonal unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Human, Non-Human Primate, Rabbit, Cat, Ferret WB, FACS, IHC (p), ICC, IP, ICFC, MS Host: Mouse Monoclonal NGFR5 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Human FACS, ELISA, ICC Host: Mouse Monoclonal 2F1C2 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) (AA 281-421) antibodyNGFR Reactivity: Human IHC, Diff, StM Host: Mouse Monoclonal rNGFR-1965 unconjugated Recombinant Antibody
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Human, Non-Human Primate IHC, Diff, StM Host: Rabbit Monoclonal NGFR-1997R unconjugated Recombinant Antibody
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Human, Mouse WB, IHC, IF, ELISA Host: Mouse Monoclonal 8G3G10 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Human, Mouse WB, IF, IHC (p) Host: Mouse Monoclonal 8G3G10 unconjugated
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Application Notes
- IHC WB FC. A concentration of 2-10 μg,ml is recommended. The optimal working concentration should be determined by the end user. This antibody may also be used for immunoabsorptive purification of NGF-receptors. See also the eLab Book at the end of this page.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in 150 μL of sterile water. Centrifuge to remove any insoluble material.
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Handling Advice
- Avoid freeze and thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Maintain the lyophilised/reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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Expiry Date
- 12 months
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- NGFR (Nerve Growth Factor Receptor (NGFR))
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Alternative Name
- p75NTR
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Background
- FUNCTION: Low affinity receptor which can bind to NGF BDNF NT-3 and NT-4. Can mediate cell survival as well as cell death of neural cells. SUBUNIT: Homodimer, disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with TRAF2 TRAF4 TRAF6 PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1 and NGFRAP1/BEX3. SUBCELLULAR LOCATION: Membrane, Single-pass type I membrane protein.
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UniProt
- P08138
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Pathways
- NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
Target
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