alpha 2 Antiplasmin antibody (AA 454-468)

Catalog No. ABIN351490

This Goat Polyclonal antibody specifically detects alpha 2 Antiplasmin in WB, IHC, ELISA and IHC (p). It exhibits reactivity toward Human.

Quick Overview for alpha 2 Antiplasmin antibody (AA 454-468) (ABIN351490)

Target: alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This alpha 2 Antiplasmin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-alpha 2 Antiplasmin Antibody

Binding Specificity: AA 454-468

Specificity: Human SERPINF2 / Alpha-2-Antiplasmin. This antibody is expected to recognise both reported isoforms (NP_000925.2, NP_001159393.1). Reported variants represent identical protein (NP_000925.2, NP_001159392.1).

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla (100%) Gibbon (93%) Horse (87%) Monkey (80%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-KDFLQSLKGFPRGDK from an internal region of human SERPINF2 / Alpha-2-Antiplasmin (NP_000925.2, NP_001159393.1). Percent identity by BLAST analysis: Human, Gorilla (100%), Gibbon (93%), Horse (87%), Monkey (80%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:16000), WB (0.3 - 1 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 3.75 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for alpha 2 Antiplasmin

Target: alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))

Alternative Name: SERPINF2 / Alpha-2-Antiplasmin

Background: Name/Gene ID: SERPINF2

Synonyms: SERPINF2, AAP, Alpha-2-plasmin inhibitor, Alpha-2-AP, Alpha-2-antiplasmin, A2AP, ALPHA-2-PI, Serpin F2, PLI, API

Gene ID: 5345

NCBI Accession: NP_000925, NP_001159393

UniProt: P08697

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones