SNCA antibody (AA 108-120)

Catalog No. ABIN352994

The Sheep Polyclonal anti-SNCA antibody is suitable to detect SNCA in samples from Human, Mouse, Rat and Dog. It has been validated for IHC.

Quick Overview for SNCA antibody (AA 108-120) (ABIN352994)

Target: SNCA (Synuclein, alpha (SNCA))

Reactivity: Human, Mouse, Rat, Dog

Host: Sheep

Clonality: Polyclonal

Conjugate: This SNCA antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-SNCA Antibody

Binding Specificity: AA 108-120

Specificity: Immunohistochemical analysis of human and rat brain indicates a high level of specificity for this antiserum. Specificity was also confirmed by western blot. Species cross-reactivity: This antiserum is known to react with human and rat alpha synuclein.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Marmoset, Squirrel monkey, Woolly monkey, Spider monkey, Mouse, Rat, Common carp, Porcine, Dog, Tamarin (100%) Orangutan, Monkey, Bovine, Horse (92%) Elephant, Rabbit (85%).

Purification: Immunoaffinity purified

Immunogen: A synthetic peptide (PQEGILEDMPVDPC) of human alpha synuclein protein (aa: 108-120) conjugated to diphtheria toxoid. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Marmoset, Squirrel monkey, Woolly monkey, Spider monkey, Mouse, Rat, Common carp, Porcine, Dog, Tamarin (100%), Orangutan, Monkey, Bovine, Horse (92%), Elephant, Rabbit (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC

Usage: Suitable for use in Immunohistochemistry.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Reconstitute in 20 μL of sterile water. Centrifuge to remove any insoluble material

Concentration: Lot specific

Buffer: Reconstitute in 20 μLof sterile water. Centrifuge to remove any insoluble material

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for SNCA

Target: SNCA (Synuclein, alpha (SNCA))

Alternative Name: SNCA / alpha-Synuclein

Background: Name/Gene ID: SNCA

Synonyms: SNCA, Alpha-synuclein, PARK4, PD1, Synuclein alpha-140, NACP, PARK1

Gene ID: 6622

UniProt: P37840

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity