TPX2 antibody

Catalog No. ABIN356359

This Mouse Monoclonal antibody specifically detects TPX2 in WB and EIA. It exhibits reactivity toward Human and Mouse.

Quick Overview for TPX2 antibody (ABIN356359)

Target: TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This TPX2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: 19AT953-286-93

Product Details anti-TPX2 Antibody

Specificity: This antibody is specific to P100.

Characteristics: Synonyms: DIL-2, C20orf1, C20orf2, HCA519, Targeting protein for Xklp2, Restricted expressionproliferation-associated protein 100, Differentially expressed in cancerous andnon-cancerous lung cells 2, Hepatocellular carcinoma-associated antigen 519

Purification: Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This monoclonal antibody is generated from mice immunized with a collection of antigenicpeptides from different regions of P100.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/1,000Western blotting: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for TPX2

Target: TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))

Alternative Name: TPX2 / DIL2

Background: The nuclear protein p100 is a proliferation-associated protein whose expression is restricted to cell cycle phases S, G2, and M. Exclusively expressed in proliferating cells from the transition G1/S until the end of cytokinesis. During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus. The full-length cDNA encodes a 747-amino acid protein with a putative ATP/GTP-binding site motif. RT-PCR analysis demonstrated strong expression of in lung carcinoma cell lines but not in normal lung tissues. Expression was also found in adult placenta, skeletal muscle, thymus, testis, and small intestine and in fetal brain, liver, and kidney. P100 is also correlated to cancer prognosis.Synonyms: C20orf1, C20orf2, DIL-2, Differentially expressed in cancerous and non-cancerous lung cells 2, HCA519, Hepatocellular carcinoma-associated antigen 519, Restricted expression proliferation-associated protein 100, Targeting protein for Xklp2

Gene ID: 22974

UniProt: Q9ULW0