FXYD1 antibody (pSer68)

Catalog No. ABIN356360

The Mouse Monoclonal anti-FXYD1 antibody has been validated for WB and EIA. It is suitable to detect FXYD1 in samples from Mouse.

Quick Overview for FXYD1 antibody (pSer68) (ABIN356360)

Target: FXYD1 (FXYD Domain Containing Ion Transport Regulator 1 (FXYD1))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This FXYD1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: 41AT858-235

Product Details anti-FXYD1 Antibody

Binding Specificity: pSer68

Specificity: This antibody is specific to PLM at Ser68.

Characteristics: Synonyms: FXYD1, PLM, FXYD domain-containing ion transport regulator 1

Purification: Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This monoclonal antibody is generated from mice immunized with a KLH conjugatedsynthetic phosphopeptide corresponding to amino acid residues surrounding Ser68 ofmouse PLM.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1: 1,000Western blotting: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for FXYD1

Target: FXYD1 (FXYD Domain Containing Ion Transport Regulator 1 (FXYD1))

Alternative Name: Phospholemman

Background: PLM (FXYD1)is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. PLM may be phosphorylated by several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity.Synonyms: FXYD domain-containing ion transport regulator 1, FXYD1, PLM

Gene ID: 56188

UniProt: Q9Z239