FXYD1 antibody (AA 1-92)

Catalog No. ABIN7267278

Product Details anti-FXYD1 Antibody

Target: FXYD1 (FXYD Domain Containing Ion Transport Regulator 1 (FXYD1))

Binding Specificity: AA 1-92

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FXYD1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: FXYD1 Rabbit pAb

Sequence: MASLGHILVF CVGLLTMAKA ESPKEHDPFT YDYQSLQIGG LVIAGILFIL GILIVLSRRC RCKFNQQQRT GEPDEEEGTF RSSIRRLSTR RR

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-92 of human FXYD1 (NP_005022.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FXYD1

Target: FXYD1 (FXYD Domain Containing Ion Transport Regulator 1 (FXYD1))

Alternative Name: FXYD1 (FXYD1 Products)

Synonyms: PLM antibody, 0610012C17Rik antibody, 1110006M24Rik antibody, Plm antibody, Pml antibody, FXYD domain containing ion transport regulator 1 antibody, FXYD domain-containing ion transport regulator 1 antibody, FXYD1 antibody, Fxyd1 antibody

Background: This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity. Transcript variants with different 5' UTR sequences have been described in the literature.,FXYD1,PLM,Cancer,Signal Transduction,Endocrine & Metabolism,Cardiovascular,Heart,Contractility,FXYD1

Molecular Weight: 10kDa

Gene ID: 5348

UniProt: O00168