TYRO3 antibody

Catalog No. ABIN356409

This anti-TYRO3 antibody is a Mouse Monoclonal antibody detecting TYRO3 in WB, IHC (p) and EIA. Suitable for Human.

Quick Overview for TYRO3 antibody (ABIN356409)

Target: TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TYRO3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 64CT15-6-2-3-1

Product Details anti-TYRO3 Antibody

Specificity: This antibody is specific to TYRO3.

Characteristics: Synonyms: BYK, DTK, RSE, SKY, Tyrosine-protein kinase receptor TYRO3

Purification: Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from mouse immunized with human recombinant TYRO3protein.

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100-1/1000. Immunohistochemistry 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for TYRO3

Target: TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

Alternative Name: TYRO3

Background: Tyrosine kinase 3,mainly expressed in brain,is involved in the protection of neurons from apoptosis. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.Synonyms: BYK, DTK, RSE, SKY, Tyrosine-protein kinase receptor TYRO3

Gene ID: 7301

UniProt: Q06418

Pathways: RTK Signaling