CEACAM5 antibody

Catalog No. ABIN356455

The Rabbit Polyclonal anti-CEACAM5 antibody is suitable to detect CEACAM5 in samples from Human. It has been validated for IHC (p) and IHC (fro).

Quick Overview for CEACAM5 antibody (ABIN356455)

Target: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEACAM5 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CEACAM5 Antibody

Specificity: This antibody recognizes CEA in several tumor tissues. Cellular localization: Luminal membrane and Cytoplasmic.

Purification: Ig Fraction

Immunogen: Human CEA purified from colon carcinoma.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry for formalin-Fixed Paraffin Embedded (FFPE) Tissue Sections andFrozen Sections: Dilute 1/100-1/200 using polymer or streptavidin approx. biotin system for 30 mins at room temperature. Positive control: Human colon cancer.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.0 mg/mL

Buffer: 10 mM PO4, 150 mM NaCl, pH 7.4 containing 0.05 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for CEACAM5

Target: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Alternative Name: CD66e / CEACAM5

Background: CEA is highly glycosylated 180 kDa glycoprotein involved in cell adhesion. It is normally produced during fetal development and then re expressed in increased amounts in colorectal, gastric, pancreatic, lung and breast carcinomas. CEA measurement is mainly used as tumor marker to identify recurrence after surgical resection.Synonyms: CEA, Carcinoembryonic antigen, Carcinoembryonic antigen-related cell adhesion molecule 5, Meconium antigen 100

Gene ID: 1048

NCBI Accession: NP_004354

UniProt: P06731