CD247 antibody (C-Term)

Catalog No. ABIN356886

The Rabbit Polyclonal anti-CD247 antibody (ABIN356886) specifically detects CD247 in WB. The antibody is reactive with Human samples.

Quick Overview for CD247 antibody (C-Term) (ABIN356886)

Target: CD247 (CD247 Molecule (CD247))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD247 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD247 Antibody

Binding Specificity: C-Term

Specificity: This antibody detects CD3Z at C-term.

Cross-Reactivity (Details): Species reactivity (expected):Pig.
Species reactivity (tested):Human.

Purification: Protein A column, followed by peptide affinity purification.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CD3Z.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA 1: 1,000. Western blot 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for CD247

Target: CD247 (CD247 Molecule (CD247))

Alternative Name: CD247 / CD3Z

Background: T-cell receptor zeta, together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response.Synonyms: CD3 zeta chain, T-cell receptor T3 zeta chain, T-cell surface glycoprotein CD3 zeta chain, T3Z, TCRZ

Molecular Weight: 18696 Da

Gene ID: 919, 9606

UniProt: P20963

Pathways: TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway