GDF3 antibody (Growth Differentiation Factor 3) (N-Term)

Details for Product anti-GDF3 Antibody No. ABIN357459, Supplier: Log in to see
Antigen
  • KFS3
  • MCOP7
  • MCOPCB6
  • C78318
  • Gdf-3
  • Vgr-2
  • Vgr2
  • ecat9
  • RGD1564178
  • CVG1
  • der
  • derriere
  • gdf3-a
  • vgr-2
  • vgr2
  • growth differentiation factor 3
  • growth differentiation factor 3 S homeolog
  • GDF3
  • Gdf3
  • gdf3.S
Epitope
N-Term
10
9
8
7
6
6
5
5
4
4
3
3
2
2
1
1
Reactivity
Human, Mouse (Murine)
91
24
7
Host
Rabbit
82
14
2
1
Clonality
Polyclonal
Conjugate
This GDF3 antibody is un-conjugated
8
5
3
3
3
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
81
47
40
16
9
6
6
6
5
1
1
1
Options
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human GDF3.
Isotype Ig Fraction
Specificity This antibody detects GDF3 at N-term.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Plasmids, Primers & others Plasmids, Primers & others GDF3 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name GDF3 (GDF3 Antibody Abstract)
Background GDF3 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. The function of this protein is unknown, but expression studies suggest it may be involved in regulation of the adult lymphatic and erythroid systems and embryonic development.Synonyms: GDF-3, Growth/differentiation factor 3
Molecular Weight 41486 Da
Gene ID 9573, 9606
UniProt Q9NR23
Application Notes ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-Growth Differentiation Factor 3 (GDF3) (N-Term) antibody (ABIN357459) anti-Growth Differentiation Factor 3 (GDF3) (N-Term) antibody
 image for anti-Growth Differentiation Factor 3 (GDF3) (N-Term) antibody (ABIN357459) anti-Growth Differentiation Factor 3 (GDF3) (N-Term) antibody (Image 2)
Background publications Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

Ducy, Karsenty: "The family of bone morphogenetic proteins." in: Kidney international, Vol. 57, Issue 6, pp. 2207-14, 2000 (PubMed).

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