POLR1C antibody (C-Term)

Catalog No. ABIN358013

The Rabbit Polyclonal anti-POLR1C antibody is suitable to detect POLR1C in samples from Human. It has been validated for WB and EIA.

Quick Overview for POLR1C antibody (C-Term) (ABIN358013)

Target: POLR1C (Polymerase (RNA) I Polypeptide C, 30kDa (POLR1C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR1C antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-POLR1C Antibody

Binding Specificity: C-Term

Specificity: This antibody detects POLR1C (C-term).

Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human POLR1C.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western Blot: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for POLR1C

Target: POLR1C (Polymerase (RNA) I Polypeptide C, 30kDa (POLR1C))

Alternative Name: POLR1C

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft.Synonyms: DNA-directed RNA polymerase I subunit C, DNA-directed RNA polymerases I and III 40 kDa polypeptide, DNA-directed RNA polymerases I and III subunit RPAC1, POLR1E, RNA polymerases I and III subunit AC1, RPA39, RPA40, RPC40

Molecular Weight: 39250 Da

Gene ID: 9533, 9606

UniProt: O15160