HSD17B10 antibody (C-Term)

Catalog No. ABIN358845

This anti-HSD17B10 antibody is a Rabbit Polyclonal antibody detecting HSD17B10 in WB, IHC (p) and EIA. Suitable for Human.

Quick Overview for HSD17B10 antibody (C-Term) (ABIN358845)

Target: HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD17B10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-HSD17B10 Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts to ABAD.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ABAD.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for HSD17B10

Target: HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

Alternative Name: HSD17B10 / ERAB

Background: Amyloid b-peptide-binding alcohol dehydrogenase (ABAD) is a member of the family of short chain dehydrogenase/reductases, unique among this family, it binds amyloid b-peptide and exhibits enzymatic activity toward a wide variety of substrates including linear alcohols. In an amyloid beta-abundant environment, ABAD appears to trigger cell stress induced by the amyloid peptide.Synonyms: 17-beta-HSD10, 17-beta-hydroxysteroid dehydrogenase 10, 3-hydroxy-2-methylbutyryl-CoA dehydrogenase, 3-hydroxyacyl-CoA dehydrogenase type II, 3-hydroxyacyl-CoA dehydrogenase type-2, Endoplasmic reticulum-associated amyloid beta-peptide-binding protein, HADH2, MRPP2, Mitochondrial Marker, Mitochondrial ribonuclease P protein 2, SCHAD, Short-chain type dehydrogenase/reductase XH98G2, Type II HADH, XH98G2

Gene ID: 3028

NCBI Accession: NP_001032900

UniProt: Q99714