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CERK antibody (C-Term)

CERK Reactivity: Human, Mouse WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN359190
  • Target See all CERK Antibodies
    CERK (Ceramide Kinase (CERK))
    Binding Specificity
    • 11
    • 7
    • 6
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 42
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 39
    • 3
    Rabbit
    Clonality
    • 42
    Polyclonal
    Conjugate
    • 24
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CERK antibody is un-conjugated
    Application
    • 26
    • 19
    • 6
    • 6
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to CERK.
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CERK.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CERK Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    CERK (Ceramide Kinase (CERK))
    Alternative Name
    Ceramide Kinase (CERK Products)
    Synonyms
    AI848610 antibody, D330016D08Rik antibody, mKIAA1646 antibody, LK4 antibody, dA59H18.2 antibody, dA59H18.3 antibody, hCERK antibody, CERK antibody, si:ch211-162i19.1 antibody, MGC81777 antibody, CG16708 antibody, DCERK antibody, Dcerk antibody, Dmel\\CG16708 antibody, dcerk antibody, ceramide kinase antibody, ceramide kinase S homeolog antibody, Ceramide kinase antibody, Cerk antibody, CERK antibody, cerk antibody, cerk.S antibody, CpipJ_CPIJ003342 antibody, LOAG_11245 antibody, LOC5579301 antibody, Bm1_50005 antibody
    Background
    Ceramide kinases convert the sphingolipid metabolite ceramide into ceramide-1-phosphate, both key mediators of cellular apoptosis and survival. Ceramide metabolism plays an essential role in the viability of neuronal cells, the membranes of which are particularly rich in sphingolipids. CERK catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. This enzyme acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8 dihydroceramide), and to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. High level expression is noted in heart, brain, skeletal muscle, kidney and liver, moderate expression in peripheral blood leukocytes and thymus, and low expression in spleen, small intestine, placenta and lung.Synonyms: Acylsphingosine kinase, KIAA1646, LK4, Lipid kinase 4, hCERK
    Gene ID
    64781, 9606
    UniProt
    Q8TCT0
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