CLASP2 antibody (C-Term)

Catalog No. ABIN359357

The Rabbit Polyclonal anti-CLASP2 antibody is suitable to detect CLASP2 in samples from Human. It has been validated for WB, IHC (p) and EIA.

Quick Overview for CLASP2 antibody (C-Term) (ABIN359357)

Target: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLASP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-CLASP2 Antibody

Binding Specificity: C-Term

Purification: Protein A Chromatography followed by peptide Affinity Purification.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CLASP2.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000Western blotting: 1/100-1/500Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for CLASP2

Target: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Alternative Name: CLASP2

Background: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.Synonyms: CLIP-associating protein 2, Cytoplasmic linker-associated protein 2, KIAA0627, Protein Orbit homolog 2, hOrbit2

Gene ID: 9606

UniProt: O75122

Pathways: Microtubule Dynamics, Maintenance of Protein Location