CAMKII gamma antibody (C-Term)

Catalog No. ABIN359402

The Rabbit Polyclonal anti-CAMKII gamma antibody is suitable to detect CAMKII gamma in samples from Human, Rat, Mouse and Primate. It has been validated for WB, IHC (p) and EIA.

Quick Overview for CAMKII gamma antibody (C-Term) (ABIN359402)

Target: CAMKII gamma (CAMK2G) (Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G))

Reactivity: Human, Rat, Mouse, Primate

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAMKII gamma antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-CAMKII gamma Antibody

Binding Specificity: C-Term

Specificity: This antibody detects CAMK2G at C-term.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-term region of human CAMK2 delta-like.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA 1: 1,000. Western blot 1: 100 - 1500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for CAMKII gamma

Target: CAMKII gamma (CAMK2G) (Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G))

Alternative Name: CAMK2G / CAMKG

Background: CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits.Synonyms: CaM kinase II subunit gamma, CaM-kinase II gamma chain, CaMK-II subunit gamma, Calcium/calmodulin-dependent protein kinase type II gamma chain

Molecular Weight: 62609 Da

Gene ID: 818

NCBI Accession: NP_751909

UniProt: Q13555

Pathways: WNT Signaling, Interferon-gamma Pathway, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of long-term Neuronal Synaptic Plasticity