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MAPK15 antibody (N-Term)

MAPK15 Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN359709
  • Target See all MAPK15 Antibodies
    MAPK15 (Mitogen-Activated Protein Kinase 15 (MAPK15))
    Binding Specificity
    • 11
    • 10
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 52
    • 17
    • 3
    Human
    Host
    • 39
    • 13
    Rabbit
    Clonality
    • 41
    • 11
    Polyclonal
    Conjugate
    • 24
    • 6
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAPK15 antibody is un-conjugated
    Application
    • 43
    • 36
    • 21
    • 13
    • 7
    • 6
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to MAPK15 (ERK8).
    Purification
    Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ERK8.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MAPK15 Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    MAPK15 (Mitogen-Activated Protein Kinase 15 (MAPK15))
    Alternative Name
    MAPK15 (MAPK15 Products)
    Synonyms
    MGC138052 antibody, MGC99048 antibody, erk7 antibody, zgc:110345 antibody, ERK7 antibody, ERK8 antibody, BC048082 antibody, Erk7 antibody, ATMPK15 antibody, F25P22.9 antibody, F25P22_9 antibody, MAP kinase 15 antibody, mitogen-activated protein kinase 15 antibody, mitogen-activated protein kinase 15 L homeolog antibody, MAP kinase 15 antibody, MAPK15 antibody, mapk15.L antibody, mapk15 antibody, Tsp_00300 antibody, Mapk15 antibody, MPK15 antibody
    Background
    The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha. Erk8 is a novel effector of RET/PTC3 and, therefore, RET biological functions.Synonyms: ERK8, Extracellular signal-regulated kinase 8, Mitogen-activated protein kinase 15
    Gene ID
    225689, 9606
    UniProt
    Q8TD08
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