CLOCK antibody (Middle Region)

Catalog No. ABIN359753

Product Details anti-CLOCK Antibody

Target: CLOCK (Clock Homolog (Mouse) (CLOCK))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLOCK antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antiobdy reacts to CLOCK.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human CLOCK.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for CLOCK

Target: CLOCK (Clock Homolog (Mouse) (CLOCK))

Alternative Name: CLOCK (CLOCK Products)

Synonyms: CG7391 antibody, CLK antibody, CLOCK antibody, Dmel\\CG7391 antibody, Jerk antibody, Jrk antibody, PAS1 antibody, bHLHe10 antibody, clk antibody, clock antibody, dCLK antibody, dCLK/JRK antibody, dCLOCK antibody, dClck antibody, dClk antibody, dClock antibody, dclk antibody, jrk antibody, Xclk antibody, XClock antibody, zCLOCK1 antibody, zfCLOCK1 antibody, 5330400M04Rik antibody, KAT13D antibody, bHLHe8 antibody, mKIAA0334 antibody, Clock antibody, clock circadian regulator antibody, clock homolog (mouse) antibody, clock circadian regulator a antibody, circadian locomotor output cycles kaput antibody, clock circadian regulator L homeolog antibody, Clk antibody, CLOCK antibody, clock antibody, clocka antibody, Clock antibody, clock.L antibody

Background: CLOCK belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within this protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1.Synonyms: BHLHE8, Circadian locomoter output cycles protein kaput, Class E basic helix-loop-helix protein 8, KIAA0334

Gene ID: 9575, 9606

UniProt: O15516

Pathways: Regulation of Lipid Metabolism by PPARalpha, Photoperiodism