PTPN7 antibody (Ser44)

Catalog No. ABIN359780

The Rabbit Polyclonal anti-PTPN7 antibody is suitable to detect PTPN7 in samples from Human. It has been validated for WB, IHC (p) and EIA.

Quick Overview for PTPN7 antibody (Ser44) (ABIN359780)

Target: PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-PTPN7 Antibody

Binding Specificity: Ser44

Specificity: This antibody reacts to PTPN7.

Purification: Protein A column, followed by peptide affinity purification

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S44 of human PTPN7.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for PTPN7

Target: PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))

Alternative Name: PTPN7 / HEPTP

Background: PTPN7 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPN7 is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP has been shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which is thought to function through dephosphorylating the molecules related to MAP kinase pathway.Synonyms: Hematopoietic protein-tyrosine phosphatase, Protein-tyrosine phosphatase LC-PTP, Tyrosine-protein phosphatase non-receptor type 7

Gene ID: 5778, 9606

UniProt: P35236