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PTPN7 antibody (Ser44)

PTPN7 Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN359780
  • Target See all PTPN7 Antibodies
    PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))
    Binding Specificity
    • 15
    • 15
    • 15
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Ser44
    Reactivity
    • 50
    • 20
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 63
    • 2
    Rabbit
    Clonality
    • 64
    • 1
    Polyclonal
    Conjugate
    • 17
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    This PTPN7 antibody is un-conjugated
    Application
    • 64
    • 39
    • 39
    • 18
    • 11
    • 10
    • 9
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to PTPN7.
    Purification
    Protein A column, followed by peptide affinity purification
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S44 of human PTPN7.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PTPN7 Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))
    Alternative Name
    PTPN7 / HEPTP (PTPN7 Products)
    Synonyms
    BPTP-4 antibody, HEPTP antibody, LC-PTP antibody, LPTP antibody, PTPNI antibody, C920001D21Rik antibody, Heptp antibody, Lcptp antibody, protein tyrosine phosphatase, non-receptor type 7 antibody, PTPN7 antibody, Ptpn7 antibody
    Background
    PTPN7 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPN7 is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP has been shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which is thought to function through dephosphorylating the molecules related to MAP kinase pathway.Synonyms: Hematopoietic protein-tyrosine phosphatase, Protein-tyrosine phosphatase LC-PTP, Tyrosine-protein phosphatase non-receptor type 7
    Gene ID
    5778, 9606
    UniProt
    P35236
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