FUCA2 antibody (N-Term)

Catalog No. ABIN359872

This Rabbit Polyclonal antibody specifically detects FUCA2 in WB, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for FUCA2 antibody (N-Term) (ABIN359872)

Target: FUCA2 (Fucosidase, alpha-L- 2, Plasma (FUCA2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUCA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-FUCA2 Antibody

Binding Specificity: N-Term

Specificity: This antibody detects FUCA2 at N-term.

Purification: Protein A Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human FUCA2.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for FUCA2

Target: FUCA2 (Fucosidase, alpha-L- 2, Plasma (FUCA2))

Alternative Name: alpha-L-Fucosidase 2

Background: Alpha-L-fucosidase catalyzes the hydrolysis of terminal alpha-L-fucosidase linkages in glycosphingolipids and glycoproteins. At least 2 separate polymorphic alpha-L-fucosidases are recognized in man. The FUCA2 locus regulates the level of alpha-fucosidase in plasma and fibroblasts but not in leukocytes. In fucosidosis, deficiency of alpha-L-fucosidase is found in both plasma and leukocytes.Synonyms: Alpha-L-fucoside fucohydrolase 2, FUCA2, PSEC0151, Plasma alpha-L-fucosidase

Gene ID: 2519, 9606

UniProt: Q9BTY2