FUCA2 antibody (N-Term)

Catalog No. ABIN391985

Product Details anti-FUCA2 Antibody

Target: FUCA2 (Fucosidase, alpha-L- 2, Plasma (FUCA2))

Binding Specificity: AA 138-167, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUCA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This FUCA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the N-terminal region of human FUCA2.

Clone: RB11941

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-FUCA2 antibody (ABIN391985)

Waidely, Al-Youbi, Bashammakh, El-Shahawi, Leblanc: "Study of the Alpha-l-Fucosidase Langmuir Monolayer at the Air-Water Interface." in: The journal of physical chemistry. B, Vol. 120, Issue 50, pp. 12843-12849, (2018) (PubMed).

Waidely, Al-Youbi, Bashammakh, El-Shahawi, Leblanc: "Alpha-l-Fucosidase Immunoassay for Early Detection of Hepatocellular Carcinoma." in: Analytical chemistry, Vol. 89, Issue 17, pp. 9459-9466, (2017) (PubMed).

Target Details for FUCA2

Target: FUCA2 (Fucosidase, alpha-L- 2, Plasma (FUCA2))

Alternative Name: FUCA2 (FUCA2 Products)

Background: Alpha-L-fucosidase catalyzes the hydrolysis of terminal alpha-L-fucosidase linkages in glycosphingolipids and glycoproteins. At least 2 separate polymorphic alpha-L-fucosidases are recognized in man. The FUCA2 locus regulates the level of alpha-fucosidase in plasma and fibroblasts but not in leukocytes. In fucosidosis, deficiency of alpha-L-fucosidase is found in both plasma and leukocytes.

Molecular Weight: 54067

Gene ID: 2519

NCBI Accession: NP_114409

UniProt: Q9BTY2