FGF10 antibody (C-Term)

Catalog No. ABIN360398

There is 1 publication for this product available. The Rabbit Polyclonal anti-FGF10 antibody is suitable to detect FGF10 in samples from Human. It has been validated for EIA and IHC (p).

Quick Overview for FGF10 antibody (C-Term) (ABIN360398)

Target: FGF10 (Fibroblast Growth Factor 10 (FGF10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF10 antibody is un-conjugated

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FGF10 Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts to FGF10.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human FGF10.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-FGF10 antibody (ABIN360398)

El Agha, Moiseenko, Kheirollahi, De Langhe, Crnkovic, Kwapiszewska, Kosanovic, Schwind, Schermuly, Henneke, MacKenzie, Quantius, Herold, Ntokou, Ahlbrecht, Morty, Günther, Seeger, Bellusci: "Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis." in: Cell stem cell, Vol. 20, Issue 2, pp. 261-273.e3, (2016) (PubMed).

Target Details for FGF10

Target: FGF10 (Fibroblast Growth Factor 10 (FGF10))

Alternative Name: FGF10

Background: FGF10 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This protein is also implicated to be a primary factor in the process of wound healing.Synonyms: FGF-10, Fibroblast growth factor 10, KGF2, Keratinocyte growth factor 2

Gene ID: 2255, 9606

UniProt: O15520

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus