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NME1 antibody (N-Term)

This Rabbit Polyclonal antibody specifically detects NME1 in WB, IHC (p) and EIA. It exhibits reactivity toward Human.
Catalog No. ABIN360544
$768.00
Plus shipping costs $50.00
0.4 mL
Shipping to: United States
Delivery in 1 to 2 Business Days

Quick Overview for NME1 antibody (N-Term) (ABIN360544)

Target

See all NME1 Antibodies
NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Reactivity

  • 133
  • 45
  • 41
  • 7
  • 5
  • 5
  • 4
  • 4
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  • 3
  • 2
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  • 1
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Human

Host

  • 94
  • 38
  • 2
  • 1
Rabbit

Clonality

  • 82
  • 52
Polyclonal

Conjugate

  • 81
  • 6
  • 6
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  • 3
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  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This NME1 antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Binding Specificity

    • 16
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    N-Term

    Specificity

    This antibody reacts to NM23 (NME1).

    Purification

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    Immunogen

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human NME1.

    Isotype

    Ig Fraction
  • Application Notes

    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target

    NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

    Alternative Name

    NDP Kinase A

    Background

    NME1 was identified because of its reduced mRNA transcript levels in highly metastatic cells. NME1 encodes the 'A' isoform of nucleoside diphosphate kinase (NDK). NDK exists as a hexamer composed of the 'A' (NME1) and 'B' (encoded by NME2) isoforms. Mutations in NME1 have been identified in aggressive neuroblastomas.Synonyms: GAAD, Granzyme A-activated DNase, NDPKA, NM23, NME1, Nucleoside diphosphate kinase A, nm23-H1

    Gene ID

    4830, 9606

    UniProt

    P15531

    Pathways

    Apoptosis, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process
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