DUSP7 antibody (N-Term)

Catalog No. ABIN360782

The Rabbit Polyclonal anti-DUSP7 antibody is suitable to detect DUSP7 in samples from Human. It has been validated for WB, IHC (p) and EIA.

Quick Overview for DUSP7 antibody (N-Term) (ABIN360782)

Target: DUSP7 (Dual Specificity Phosphatase 7 (DUSP7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-DUSP7 Antibody

Binding Specificity: N-Term

Specificity: This antibody reacts to DUSP7.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human DUSP7.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western Blot: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for DUSP7

Target: DUSP7 (Dual Specificity Phosphatase 7 (DUSP7))

Alternative Name: DUSP7 / PYST2

Background: DUSP7 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP)kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associatedwith cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.Synonyms: Dual specificity protein phosphatase 7

Gene ID: 1849, 9606

UniProt: Q16829

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades