IL9 Receptor antibody (Extracellular Domain)

Catalog No. ABIN360910

This Rat Monoclonal antibody specifically detects IL9 Receptor in WB. It exhibits reactivity toward Mouse.

Quick Overview for IL9 Receptor antibody (Extracellular Domain) (ABIN360910)

Target: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL9 Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 12F43

Product Details anti-IL9 Receptor Antibody

Binding Specificity: Extracellular Domain

Specificity: This antibody detects Mouse IL-9R. Other species not tested.

Purification: Protein A/G Affinity Chromatography

Immunogen: Recombinant protein of IL-6R extracellular domain

Isotype: IgG2

Application Details

Application Notes: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Buffer: PBS, None

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for IL9 Receptor

Target: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Alternative Name: CD129 / IL9R

Background: Human Interleukin 9 (IL9) was first identified based on its proliferative activity on a human myeloid leukemic cell line. Human IL9 stimulates the proliferation of the human megakaryocytic leukemic cell line M07e. Human IL9 supports erythroid colony formation and synergizes with IL4 in the production of IgE and IgG. The interleukin 9 receptor is a member of the hematopoietin receptor superfamily. The cDNAs encoding mouse and human IL9 receptors have been isolated. The deduced mouse and human transmembrane proteins, sharing 53 % amino acid sequence identity, contain 468 and 533 amino acid residues, respectively. A number of isoforms of IL9R, including a putative soluble form, have also been identified. The IL9 receptor is expressed in a variety of hematopoietic cells including T cells, neutrophils, mast cells, and macrophages.Synonyms: IL-9 receptor, IL-9R, Interleukin-9 receptor

Gene ID: 16199

NCBI Accession: NP_032400

UniProt: Q01114

Pathways: JAK-STAT Signaling, Growth Factor Binding