IL15RA antibody (Extracellular Domain)

Catalog No. ABIN360913

This Rat Monoclonal antibody specifically detects IL15RA in WB. It exhibits reactivity toward Mouse.

Quick Overview for IL15RA antibody (Extracellular Domain) (ABIN360913)

Target: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL15RA antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 6C38

Product Details anti-IL15RA Antibody

Binding Specificity: Extracellular Domain

Specificity: This antibody detects IL-15Ralpha. No cross activity to other IGFBPs.

Purification: Protein A/G affinity chromatography

Immunogen: Recombinant protein of IL-15Ralpha extracellular domain.

Isotype: IgG2

Application Details

Application Notes: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for IL15RA

Target: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Alternative Name: IL15RA

Background: IL15RA is a cytokine receptor that specifically binds IL15 with high affinity. It shares two subunits with the receptor of IL2, the IL2R beta and IL2R gamma chains. This forms the basis of many overlapping biological activities of IL15 and IL2. The IL2 receptor requires an additional IL2-specific alpha subunit for high affinity IL2 binding. This protein is structurally related to IL2R alpha, but is capable of binding IL15 with high affinity independent of other subunits, which suggests the distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. There are nine different isoforms.Synonyms: IL-15R-alpha, IL-15RA, Interleukin-15 receptor subunit alpha

Gene ID: 16169

NCBI Accession: NP_032384

UniProt: Q60819

Pathways: JAK-STAT Signaling