IL17RA antibody (Extracellular Domain)

Catalog No. ABIN360914

The Rat Monoclonal anti-IL17RA antibody is suitable to detect IL17RA in samples from Mouse. It has been validated for WB.

Quick Overview for IL17RA antibody (Extracellular Domain) (ABIN360914)

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL17RA antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 10B27

Product Details anti-IL17RA Antibody

Binding Specificity: Extracellular Domain

Specificity: This antibody detects IL-17R. No cross activity to IL-17B R.

Purification: Protein A/G affinity chromatography

Immunogen: Recombinant protein of IL-17R extracellular domain.

Isotype: IgG2

Application Details

Application Notes: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for IL17RA

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Alternative Name: CD217 / IL17RA

Background: Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. [provided by RefSeq]Synonyms: CDw217, IL-17 receptor, IL17R, Interleukin-17 receptor A

Gene ID: 16172

NCBI Accession: NP_032385

UniProt: Q60943

Pathways: SARS-CoV-2 Protein Interactome