IL23R antibody (Extracellular Domain)

Catalog No. ABIN360919

This Rat Monoclonal antibody specifically detects IL23R in WB. It exhibits reactivity toward Mouse.

Quick Overview for IL23R antibody (Extracellular Domain) (ABIN360919)

Target: IL23R (Interleukin 23 Receptor (IL23R))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL23R antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 6D34

Product Details anti-IL23R Antibody

Binding Specificity: Extracellular Domain

Specificity: This antibody detects IL-23R.

Purification: Protein A/G Affinity Chromatography.

Immunogen: Recombinant protein of IL-23R extracellular domain.

Isotype: IgG2

Application Details

Application Notes: Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 0.5 mg/mL.

Buffer: PBS without preservatives or stabilizers.

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for IL23R

Target: IL23R (Interleukin 23 Receptor (IL23R))

Alternative Name: Interleukin-23 Receptor / IL23R

Background: The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.Synonyms: IL-23 receptor, IL-23R

Gene ID: 209590

NCBI Accession: NP_653131

UniProt: Q8K4B4

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation