MAP2 antibody

Catalog No. ABIN361345

This Chicken Polyclonal antibody specifically detects MAP2 in WB, IHC, ELISA and ICC. It exhibits reactivity toward Cow and has been mentioned in 7+ publications.

Quick Overview for MAP2 antibody (ABIN361345)

Target: MAP2 (Microtubule-Associated Protein 2 (MAP2))

Reactivity: Cow

Host: Chicken

Clonality: Polyclonal

Conjugate: This MAP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Product Details anti-MAP2 Antibody

Specificity: Specific for endogenous levels of the ~280 kDa MAP2 protein.

Cross-Reactivity: Cow, Human, Mouse, Rat

Sensitivity: The antibody has been directly tested for reactivity in bovine, human, mouse and rat. It is expected that the antibody will react with other mammalian tissues.

Characteristics: Our Anti-Microtubule Associated Protein 2 (MAP2) Antibody primary antibody is chicken polyclonal. It detects Microtubule Associated Protein 2 (MAP2) and is total igy fraction. It is great for use in ELISA, WB, IHC, ICC.

Purification: Total IgY fraction.

Immunogen: Recombinant bovine MAP2 protein expressed in and purified from E. Coli.

Isotype: IgY

Application Details

Application Notes:

Dilution Range: ICC: 1:1000-1:20,000

Dilution Range: WB: 1:20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 19 mg/mL

Buffer: PBS + 10 mM Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Expiry Date: 12 months

References for anti-MAP2 antibody (ABIN361345)

Willim, Woike, Greene, Das, Pfeifer, Yuan, Lindsey, Itani, Böhme, Tibbe, Hönck, Hassani Nia, Zech, Brunet, Faivre, Sorlin, Vitobello, Smol, Colson, Baranano, Schatz, Bayat, Schoch, Spillmann, Davis, Conboy, Vetrini, Platzer, Neuser, Gburek-Augustat, Grace: "Variants in LRRC7 lead to intellectual disability, autism, aggression and abnormal eating behaviors." in: Nature communications, Vol. 15, Issue 1, pp. 7909, (2024) (PubMed).

Woike, Tibbe, Hassani Nia, Martens, Wang, Barsukov, Kreienkamp: "The Shank/ProSAP N-Terminal (SPN) Domain of Shank3 Regulates Targeting to Postsynaptic Sites and Postsynaptic Signaling." in: Molecular neurobiology, Vol. 61, Issue 2, pp. 693-706, (2024) (PubMed).

Woike, Wang, Tibbe, Hassani Nia, Failla, Kibæk, Overgård, Larsen, Fagerberg, Barsukov, Kreienkamp: "Mutations affecting the N-terminal domains of SHANK3 point to different pathomechanisms in neurodevelopmental disorders." in: Scientific reports, Vol. 12, Issue 1, pp. 902, (2022) (PubMed).

Hassani Nia, Woike, Bento, Niebling, Tibbe, Schulz, Hirnet, Skiba, Hönck, Veith, Günther, Scholz, Bierhals, Driemeyer, Bend, Failla, Lohr, Alai, Kreienkamp: "Structural deficits in key domains of Shank2 lead to alterations in postsynaptic nanoclusters and to a neurodevelopmental disorder in humans." in: Molecular psychiatry, (2022) (PubMed).

Hassani Nia, Woike, Martens, Klüssendorf, Hönck, Harder, Kreienkamp: "Targeting of δ-catenin to postsynaptic sites through interaction with the Shank3 N-terminus." in: Molecular autism, Vol. 11, Issue 1, pp. 85, (2021) (PubMed).

Hassani Nia, Woike, Kloth, Kortüm, Kreienkamp: "Truncating mutations in SHANK3 associated with global developmental delay interfere with nuclear β-catenin signaling." in: Journal of neurochemistry, (2020) (PubMed).

Ho, Dallalzadeh, Karathanasis, Keles, Vangala, Grogan, Poirazi, Martin: "GluA2 mRNA distribution and regulation by miR-124 in hippocampal neurons." in: Molecular and cellular neurosciences, Vol. 61, pp. 1-12, (2014) (PubMed).

Target Details for MAP2

Target: MAP2 (Microtubule-Associated Protein 2 (MAP2))

Alternative Name: MAP2

Background:

Synonyms: DKFZp686I2148 antibody, MAP 2 antibody, MAP dendrite specific antibody, MAP-2 antibody, MAP2 antibody, MAP2A antibody, MAP2B antibody, MAP2C antibody, Microtubule associated protein 2 antibody, Microtubule-associated protein 2 antibody, MTAP2_HUMAN antibody

Description Logic: Our Anti-Microtubule Associated Protein 2 (MAP2) Antibody primary antibody is chicken polyclonal. It detects Microtubule Associated Protein 2 (MAP2) and is total igy fraction. It is great for use in ELISA, WB, IHC, ICC.

Gene Name Alternatives: MAP2

Molecular Weight: 280 kDa

Gene ID: 4133

UniProt: P11137