DDC antibody (N-Term)

Catalog No. ABIN361425

Product Details anti-DDC Antibody

Target: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDC antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Specific for the ~55k DDC protein.

Cross-Reactivity: Cow (Bovine), Dog (Canine), Guinea Pig, Human, Rabbit, Rat (Rattus), Sheep (Ovine)

Purification: Antigen Affinity Purified from Pooled Serum

Immunogen: Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH

Application Details

Application Notes: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Storage: -20 °C

Target Details for DDC

Target: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Alternative Name: DDC (DDC Products)

Synonyms: AADC antibody, wu:fa56d05 antibody, wu:fd59h03 antibody, wu:fk20h01 antibody, zgc:65801 antibody, zgc:76929 antibody, Ddc antibody, DdcDv antibody, Dvir\\GJ17995 antibody, GJ17995 antibody, dvir_GLEANR_2561 antibody, Aadc antibody, 5-HT antibody, CG10697 antibody, DDC antibody, DdcDm antibody, Dmel\\CG10697 antibody, ddc antibody, fDDC antibody, l(2)37Bl antibody, l(2)37Ch antibody, l(2)k02104 antibody, dopa decarboxylase antibody, Dopa-decarboxylase antibody, dopa decarboxylase (aromatic L-amino acid decarboxylase) antibody, Dopa decarboxylase antibody, dopa decarboxylase L homeolog antibody, DDC antibody, ddc antibody, Ddc antibody, Dvir\Ddc antibody, ddc.L antibody

Background: DOPA decarboxylase (aromatic L-amino acid decarboxylase, AADC, DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002, Berry et al., 1996, Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001, Zhu et al., 2000, Zhu et al., 1999). Anti-DOPA Decarboxylase Western blot of 5 (g of bovine adrenal medulla lysate showing specific immunolabeling of the ~55k DOPA decarboxylase protein.

Molecular Weight: '55 kDa

Gene ID: 1644

UniProt: P20711

Pathways: Dopaminergic Neurogenesis