Tryptophan Hydroxylase 2 antibody (pSer19)

Catalog No. ABIN361498

This Rabbit Polyclonal antibody specifically detects Tryptophan Hydroxylase 2 in WB and ELISA. It exhibits reactivity toward Ratand has been mentioned in 1 publication.

Quick Overview for Tryptophan Hydroxylase 2 antibody (pSer19) (ABIN361498)

Target: Tryptophan Hydroxylase 2 (TPH2)

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tryptophan Hydroxylase 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Tryptophan Hydroxylase 2 Antibody

Binding Specificity: pSer19

Specificity: Specific for endogenous levels of the ~55 kDa tryptophan hydroxylase protein phosphorylated at Ser19 .

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: bovine, mouse, zebra fish

Characteristics: Our Tryptophan Hydroxylase (Ser19) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects Tryptophan Hydroxylase (Ser19) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Purification: Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser19 of rat tryptophan hydroxylase 2 (TPH2), conjugated to keyhole limpet hemocyanin (KLH).

Isotype: IgG

Application Details

Application Notes: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Storage: -20 °C

Storage Comment: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Expiry Date: 12 months

References for anti-Tryptophan Hydroxylase 2 antibody (ABIN361498)

Matsuo, Izumi, Wakita, Kume, Takada-Takatori, Sawada, Akaike: "Haloperidol, spiperone, pimozide and aripiprazole reduce intracellular dopamine content in PC12 cells and rat mesencephalic cultures: implication of inhibition of vesicular transport." in: European journal of pharmacology, (2010) (PubMed).

Target Details for Tryptophan Hydroxylase 2

Target: Tryptophan Hydroxylase 2 (TPH2)

Alternative Name: TPH2

Background:

Synonyms: MGC138871 antibody, ADHD7 antibody, FLJ37295 antibody, MGC138872 antibody, Neuronal tryptophan hydroxylase antibody, NTPH antibody, TPH 2 antibody, Tph2 antibody, TPH2 antibody, TPH2_HUMAN antibody, Tryptophan 5-hydroxylase 2 antibody, Tryptophan 5-monooxygenase 2 antibody, Tryptophan hydroxylase 2 antibody

Description Logic: Our Tryptophan Hydroxylase (Ser19) rabbit polyclonal phosphospecific primary antibody is produced . It detects Tryptophan Hydroxylase (Ser19) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Gene Name Alternatives: TPH2

Molecular Weight: 55 kDa

Gene ID: 317675

UniProt: Q8CGU9