Synaptotagmin antibody (pSer309)

Catalog No. ABIN362242

The Rabbit Polyclonal anti-Synaptotagmin antibody (ABIN362242) specifically detects Synaptotagmin in IF. The antibody is reactive with Rat, Mouse and Human samples.

Quick Overview for Synaptotagmin antibody (pSer309) (ABIN362242)

Target: Synaptotagmin (SYT)

Reactivity: Rat, Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Synaptotagmin antibody is un-conjugated

Application: Immunofluorescence (IF)

Product Details anti-Synaptotagmin Antibody

Binding Specificity: pSer309

Specificity: The antibody detects endogenous level of Synaptotagmin only when phosphorylated at serine 309.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Immunogen: Peptide sequence around phosphorylation site of pSer309 (G-L-S (p) -D-P) derived from Human. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Isotype: IgG

Application Details

Application Notes: Immunofluorescence: 1:100-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for Synaptotagmin

Target: Synaptotagmin (SYT)

Alternative Name: Synaptotagmin

Background: The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse

Molecular Weight: 46 kDa

NCBI Accession: NP_001129

UniProt: P21579