JAK2 antibody (AA 568-572)
Quick Overview for JAK2 antibody (AA 568-572) (ABIN363094)
Target
See all JAK2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 568-572
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Specificity
- The antibody detects endogenous level of total Jak2 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen .
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Immunogen
- Peptide sequence around AA 568-572 (G-D-Y-G-Q) derived from Human JAK2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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Isotype
- IgG
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Application Notes
- Immunohistochemistry: 1:50-1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- JAK2 (Janus Kinase 2 (JAK2))
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Alternative Name
- Jak2
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Background
- Plays a role in leptin signaling and control of body weight.
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Molecular Weight
- 125 kDa
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NCBI Accession
- NP_004963
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UniProt
- O60674
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Pathways
- JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
Target
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