Paxillin antibody (AA 86-90)

Catalog No. ABIN363106

This anti-Paxillin antibody is a Rabbit Polyclonal antibody detecting Paxillin in WB and IF. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for Paxillin antibody (AA 86-90) (ABIN363106)

Target: Paxillin (PXN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Paxillin antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Paxillin Antibody

Binding Specificity: AA 86-90

Specificity: The antibody detects endogenous level of total Paxillin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen .

Immunogen: Peptide sequence around AA 86-90 (P-V-Y-G-S) derived from Human Paxillin. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Isotype: IgG

Application Details

Application Notes: Western blotting: 1:500-1:1000
Immunofluorescence: 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

References for anti-Paxillin antibody (ABIN363106)

Wang, Bi, Ampah, Zhang, Li, Jiao, Wang, Ba, Zeng: "Lipid raft regulates the initial spreading of melanoma A375 cells by modulating ?1 integrin clustering." in: The international journal of biochemistry & cell biology, Vol. 45, Issue 8, pp. 1679-89, (2013) (PubMed).

Target Details for Paxillin

Target: Paxillin (PXN)

Alternative Name: Paxillin

Background: Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).

Molecular Weight: 68 kDa

NCBI Accession: NP_001074

UniProt: P49023

Pathways: MAPK Signaling, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling