BRCA1 antibody (AA 1314-1600, AA 1314-1864)

Catalog No. ABIN363286

Product Details anti-BRCA1 Antibody

Target: BRCA1 (Breast Cancer 1 (BRCA1))

Binding Specificity: AA 1314-1600, AA 1314-1864

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BRCA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Specificity: Reacts with human BRCA1

Purification: Purified (protein G)

Immunogen: Human BRCA1 residues 1314-1864. The epitope recognized is found between amino acids 1314-1600.

Clone: MU

Isotype: IgG2b kappa

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
WB (2 - 4 μg/mL) FC(1 μg per 10^6 cells) IP(1:10 - 1:500)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.9 mg/mL

Buffer: Tris-glycine, NaCl 150 mM, Sodium azide 0.05 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C/-80 °C

Storage Comment: Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Target Details for BRCA1

Target: BRCA1 (Breast Cancer 1 (BRCA1))

Alternative Name: Breast Cancer Type 1 Susceptibility Protein (BRCA1 Products)

Gene ID: 672

UniProt: P38398

Pathways: Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus