Pyruvate Dehydrogenase Kinase (AA 350-436), (C-Term) antibody

Catalog No. ABIN363520

Product Details

Target: Pyruvate Dehydrogenase Kinase

Binding Specificity: AA 350-436, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: Reacts with the human PDK1

Cross-Reactivity: Mouse (Murine), Chicken, Rat (Rattus)

Cross-Reactivity (Details): Predicted to cross react with mouse (100 % ), rat (100 %), chicken (93 %).

Purification: Purified

Immunogen: Synthetic peptide made to a C-Terminal portion of the human PDK1 protein sequence (between residues 350-436)

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
ICC/IF1:1000-1:2000 WB2 μg/mL

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: Tris-glycine, NaCl 150 mM buffer, Sodium azide 0.05 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C/-80 °C

Storage Comment: Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Target Details

Target: Pyruvate Dehydrogenase Kinase

Background: Pyruvate dehydrogenase kinase isoform 1 (PDK1) inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.

Gene ID: 5163