YAP1 antibody

Catalog No. ABIN363591

The Rabbit Polyclonal anti-YAP1 antibody (ABIN363591) specifically detects YAP1 in WB, IF, IHC (p), IP and ICC. The antibody is reactive with Human and Mouse samples.

Quick Overview for YAP1 antibody (ABIN363591)

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Product Details anti-YAP1 Antibody

Specificity: Reacts with human and mouse YAP1

Purification: Antigen affinity purified

Immunogen: Recombinant YAP protein expressed in bacteria

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
ICC/IF1:500, IHC1:50-1:200, IHC-P1:50-1:200, IP2-10 μg, WB1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS, glycerol 15 % , Sodium azide 0.02 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C/-80 °C

Storage Comment: Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Target Details for YAP1

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Alternative Name: Yorkie Homolog (YAP1)

Background: Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

Gene ID: 10413

Pathways: MAPK Signaling, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha