Progesterone Receptor antibody (C-Term)

Catalog No. ABIN364377

This anti-Progesterone Receptor antibody is a Rabbit Polyclonal antibody detecting Progesterone Receptor in IHC and IHC (p). Suitable for Human.

Quick Overview for Progesterone Receptor antibody (C-Term) (ABIN364377)

Target: Progesterone Receptor (PGR)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Progesterone Receptor antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Progesterone Receptor Antibody

Binding Specificity: C-Term

Brand: IHC-plus™

Specificity: Synthetic peptide

Purification: Purified

Immunogen: Peptide derived from C-terminus of inhibitory domain (IF) of human porgesterone receptor.

Application Details

Application Notes: Approved: IHC, IHC-P (20 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 20 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 20 mM Tris-HCl,  pH 8.0, 20 mg/mL BSA, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to Avoid freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot to avoid freeze/thaw cycles.

Target Details for Progesterone Receptor

Target: Progesterone Receptor (PGR)

Alternative Name: PGR/PR/Progesterone Receptor

Background: Name/Gene ID: PGR
Subfamily: NR3 Steroid receptor
Family: NHR

Synonyms: PGR, NR3C3, PR, Progesterone receptor

Gene ID: 5241

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration