IL-5 antibody (Biotin)

Catalog No. ABIN371619

This anti-IL-5 antibody is a Rat Monoclonal antibody detecting IL-5 in EIA, ELISA (Capture) and ELISA (Detection). Suitable for Human.

Quick Overview for IL-5 antibody (Biotin) (ABIN371619)

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-5 antibody is conjugated to Biotin

Application: Enzyme Immunoassay (EIA), ELISA (Capture), ELISA (Detection)

Clone: JES1-5A10

Product Details anti-IL-5 Antibody (Biotin)

Specificity: This antibody is specific to Human Interleukin-5/IL-5. (Ref.1-4)

Characteristics: Synonyms: IL-5, B-cell differentiation factor I, Eosinophil differentiation factor, T-cell replacing factor,TRF

Immunogen: COS-expressed recombinant human IL-5.

Isotype: IgG2a

Application Details

Application Notes: ELISA: Useful useful as a Detection/Capture antibody in a Sandwich ELISA for quantifyinghuman IL-5 protein levels. (Ref.1-5)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for IL-5

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Alternative Name: Interleukin-5 / IL5

Background: Human Interleukin 5 (IL5) is a cytokine produced primarily by activated T lymphocytes. It exists as an antiparallel disulfide-linked homodimeric glycoprotein with 115 amino-acid residues in each chain. Known also as EDG (eosinophil differentiating factor), functions predominantly as an eosinophilopoietic factor. Analysis of its crystal structure reveals a novel two-domain structure, with each domain showing significant homology to the cytokine fold in GM-CSF, M-CSF, IL2, IL4 and growth hormone. Human and Mouse IL5 have 70 % amino acid sequence homology.Synonyms: B-cell differentiation factor I, Eosinophil differentiation factor, IL-5, T-cell replacing factor, TRF

Gene ID: 3567

UniProt: P05113

Pathways: JAK-STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour