EPH Receptor A2 antibody (AA 450-500)

Catalog No. ABIN372265

This Rabbit Polyclonal antibody specifically detects EPH Receptor A2 in WB and IHC (p). It exhibits reactivity toward Human, Mouse, Rat, Monkey, Dog, Cow, Horse and Chimpanzee.

Quick Overview for EPH Receptor A2 antibody (AA 450-500) (ABIN372265)

Target: EPH Receptor A2 (EPHA2)

Reactivity: Human, Mouse, Rat, Monkey, Dog, Cow, Horse, Chimpanzee

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor A2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-EPH Receptor A2 Antibody

Binding Specificity: AA 450-500

Specificity: This antibody recognizes Ephrin Type A Receptor 2 (EPHA2).

Cross-Reactivity (Details): Species reactivity (expected):Bovine, Chimpanzee, Canine (Dog), Horse, Monkey, Mouse and Rat.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding to a portion of the amino acids 450-500 of Human EphA2.

Isotype: IgG

Application Details

Application Notes: Western Blot: 0.5-2.0 μg/mL. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % Sodium Azide as preservative and 0.2 % Gelatin as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for EPH Receptor A2

Target: EPH Receptor A2 (EPHA2)

Alternative Name: EPHA2 / ECK

Background: EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.Synonyms: Eph receptor A2, Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK

Molecular Weight: 108 kDa.

Gene ID: 1969

NCBI Accession: NP_004422

UniProt: P29317

Pathways: RTK Signaling