Derlin-3 antibody (N-Term)
Quick Overview for Derlin-3 antibody (N-Term) (ABIN372297)
Target
See all Derlin-3 (DERL3) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Specificity
- This antibody recognizes Derlin-3/DERL3 (N-term).
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Cross-Reactivity (Details)
- Species reactivity (tested):Human.
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Purification
- Immunoaffinity Chromatography.
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Immunogen
- Synthetic peptide corresponding to N-terminal residues of Human DERL3 (Derlin-3).
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Isotype
- IgG
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Application Notes
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Immunohistochemistry on Paraffin Sections: 20 μg/mL. Western Blot: 1 μg/mL. ELISA: 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS containing 0.01 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Derlin-3 (DERL3) (Der1-Like Domain Family, Member 3 (DERL3))
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Alternative Name
- Derlin-3
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Background
- DERL3 (Derlin-3) may be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins. Its precise role is however unclearSynonyms: C22orf14, DER3, DERL3, Degradation in endoplasmic reticulum protein 3, Der1-like protein 3, LLN2
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Molecular Weight
- 27 kDa.
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Gene ID
- 91319
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NCBI Accession
- NP_001002862
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UniProt
- Q96Q80
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Pathways
- ER-Nucleus Signaling
Target
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