Endoglin antibody (AA 26-176)

Catalog No. ABIN372489

This anti-Endoglin antibody is a Rabbit Polyclonal antibody detecting Endoglin in IHC (p) and EIA. Suitable for Human.

Quick Overview for Endoglin antibody (AA 26-176) (ABIN372489)

Target: Endoglin (ENG)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Endoglin antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-Endoglin Antibody

Binding Specificity: AA 26-176

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogen: Recombinant protein encoding amino acids 26-176 of Human CD105.

Isotype: IgG

Application Details

Application Notes: ELISA. Immunohistochemistry on Paraffin Sections: (1/100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: 10 mM PBS, pH 7.6 containing 0.2 % BSA as stabilizer and 15 mM Sodium Azide as preservative, before the addition of Glycerol to 40 %

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for Endoglin

Target: Endoglin (ENG)

Alternative Name: CD105 / Endoglin

Background: CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.Synonyms: END, ENG, HHT1, ORW, ORW1

Gene ID: 9606

UniProt: P17813