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RPH3A antibody (C-Term)
RPH3A
Reactivity: Human, Mouse, Rat, Dog, Cow, Non-Human Primate
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-RPH3A Antibody
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Target
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RPH3A
(Rabphilin 3A (RPH3A))
Binding Specificity
All epitopes for RPH3A antibodies
C-Term
Reactivity
All reactivities for RPH3A antibodies
Human, Mouse, Rat, Dog, Cow, Non-Human Primate
Host
All hosts for RPH3A antibodies
Rabbit
Clonality
All clonalities for RPH3A antibodies
Polyclonal
Conjugate
All conjugates for RPH3A antibodies
This RPH3A antibody is un-conjugated
Application
All applications for RPH3A antibodies
Western Blotting (WB)
Specificity
This antibody recognizes the ~82k Rabphilin-3A protein.
Cross-Reactivity (Details)
Species reactivity (expected):Human, Bovine, Canine and non-Human Primates. Species reactivity (tested):Rat.
Purification
Affinity Chromatography.
Immunogen
Synthetic peptide corresponding to amino acid residues from the C-terminal region of Rabphilin-3A.
Isotype
IgG
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Discover our top product RPH3A Primary Antibody
Alternatives
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Application Details
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Application Notes
Western blot: 1/1,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store the antibody undiluted (in aliquots) at-20 °C.
Target Details for RPH3A
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Target
RPH3A
(Rabphilin 3A (RPH3A))
Alternative Name
Rabphilin-3A / RPH3A (RPH3A Products )
Synonyms
2900002P20Rik antibody, AU022689 antibody, AW108370 antibody, CG11556 antibody, Dmel\\CG11556 antibody, exophilin-1 antibody, fc61h10 antibody, rph3a antibody, wu:fc61h10 antibody, rabphilin 3A antibody, Rabphilin antibody, rabphilin-3a, putative antibody, rabphilin-3A antibody, rabphilin 3A S homeolog antibody, rabphilin 3A homolog (mouse), a antibody, RPH3A antibody, Rph3a antibody, Rph antibody, Smp_145120 antibody, Tsp_00335 antibody, rph3a.S antibody, rph3aa antibody
Background
Rabphilin-3A is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes (Geppert et al., 1994,Li et al., 1994). The expression of rabphilin 3A is reduced in an animal model of Huntington's disease (Smith et al., 2005). Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner (Fykse et al., 1995,Foletti and Scheller, 2001).Synonyms: Exophilin 1, Exophilin-1, KIAA0985, Rabphilin 3A
Gene ID
171039
NCBI Accession
NP_598202
UniProt
P47709
Pathways
Synaptic Vesicle Exocytosis
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