MTM1 antibody (C-Term)

Catalog No. ABIN374119

This Goat Polyclonal antibody specifically detects MTM1 in WB. It exhibits reactivity toward Human and Cow.

Quick Overview for MTM1 antibody (C-Term) (ABIN374119)

Target: MTM1 (Myotubularin 1 (MTM1))

Reactivity: Human, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This MTM1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MTM1 Antibody

Binding Specificity: C-Term

Specificity: This antibody detects MTM1 at C-term.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Canine (Dog), Bovine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: eptide with sequence C-SSPSQMMPHVQTHF, from the C Terminus of the protein sequence Genename: MTM1

Application Details

Application Notes: Peptide ELISA: 1/16000. Western blot: 0.3 - 1 μg/mL. Approx 70 kDa band observed in lysates of Human SkeletalMuscle and of cell line HepG2 (calculated MW of 69.0 kDa according to NP_000243.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MTM1

Target: MTM1 (Myotubularin 1 (MTM1))

Alternative Name: Myotubularin / MTM1

Background: Dual-specificity phosphatase that acts on both phosphotyrosine and phosphoserine. Could be involved in a signal transduction pathway necessary for late myogenesis, although its ubiquitous expression suggests a wider function.

Gene ID: 4534

NCBI Accession: NP_000243

UniProt: Q13496

Pathways: Inositol Metabolic Process, Skeletal Muscle Fiber Development