Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) (N-Term) antibody

Details for Product No. ABIN374418
Antigen
  • SMUG1
  • xsmug1
  • 1200013B09Rik
  • A930006H09Rik
  • C85220
  • FDG
  • HMUDG
  • UNG3
  • single-strand-selective monofunctional uracil-DNA glycosylase 1
  • single-strand selective monofunctional uracil DNA glycosylase
  • single-strand-selective monofunctional uracil-DNA glycosylase 1 L homeolog
  • SMUG1
  • smug1
  • smuG1
  • smuG
  • LOC5577584
  • CpipJ_CPIJ002767
  • Smug1
  • smug1.L
Epitope
N-Term
17
10
7
7
5
3
2
2
2
1
1
1
1
Reactivity
Human
68
28
26
7
2
2
1
1
1
1
1
Host
Goat
55
7
6
Clonality
Polyclonal
Conjugate
Un-conjugated
5
4
4
3
3
3
1
1
1
1
1
1
Application
Western Blotting (WB)
59
36
8
7
4
3
2
2
1
1
1
Options
Immunogen Peptide from the N Terminus of the protein sequence according to NP_055126.1 Genename: SMUG1
Sequence PQAFLLGSIH EPA-C
Specificity This antibody detects SMUG1 at N-term.
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
Antigen
Alternative Name SMUG1 (SMUG1 Antibody Abstract)
Background Synonyms: Single-strand selective monofunctional uracil DNA glycosylase
Gene ID 23583
NCBI Accession NP_055126
UniProt Q53HV7
Pathways DNA Damage Repair
Application Notes Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.5-2 μg/mL. Approx 35 kDa band observed in Molt-4 lysates (predicted MW of35 kDa according to NP_055126.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
Supplier Images
Image no. 1 for anti-Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) (N-Term) antibody (ABIN374418) anti-Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) (N-Term) antibody
Background publications Boorstein, Cummings, Marenstein, Chan, Ma, Neubert, Brown, Teebor: "Definitive identification of mammalian 5-hydroxymethyluracil DNA N-glycosylase activity as SMUG1." in: The Journal of biological chemistry, Vol. 276, Issue 45, pp. 41991-7, 2001 (PubMed).

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