FHL1 antibody (Internal Region)

Catalog No. ABIN374472

The Goat Polyclonal anti-FHL1 antibody (ABIN374472) specifically detects FHL1 in WB. The antibody is reactive with Human and Pig samples.

Quick Overview for FHL1 antibody (Internal Region) (ABIN374472)

Target: FHL1 (Four and A Half LIM Domains 1 (FHL1))

Reactivity: Human, Pig

Host: Goat

Clonality: Polyclonal

Conjugate: This FHL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FHL1 Antibody

Binding Specificity: Internal Region

Specificity: This antibody reacts to FHL1.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Canine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence CTVSRVSHPVSKARK, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/128000. Western blot: 0.01 - 0.1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FHL1

Target: FHL1 (Four and A Half LIM Domains 1 (FHL1))

Alternative Name: FHL1

Background: FHL1 (SLIM 1) is a LIM domain protein transcript that is preferentially expressed in postnatal skeletal muscle but little is known about its function in this tissue. LIM proteins, (named for 'LIN11, ISL1 and MEC3') are defined by the possession of a highly conserved double zinc finger motif called the LIM domain. FHL1 may have an involvement in muscle development or hypertrophy. Isoform 2 binds to RBP J and plays a negative regulatory role in the RBP J mediated transcription in mammalian systems.Synonyms: FHL-1, FHL1, Four and a half LIM domains protein 1, SLIM, SLIM-1, SLIM1, Skeletal Muscle LIM-protein 1

Gene ID: 2273

NCBI Accession: NP_001153171

UniProt: Q13642